大气颗粒物污染对人群心脑血管疾病死亡急性效应的Meta分析

被引：43

作者：

陈慧 ^{[1
,2
]}

王建生 ^{[2
]}

尚琪 ^{[3
]}

机构：

[1] 北京协和医学院公共卫生学院

[2] 环境保护部环境发展中心

[3] 中国疾病预防控制中心环境与健康相关产品安全所

来源：

环境与健康杂志 | 2013年 / 30卷 / 05期

关键词：

大气污染; 颗粒物; 心脑血管疾病; 死亡率; Meta分析;

D O I：

10.16241/j.cnki.1001-5914.2013.05.008

中图分类号：

X503.1 [对人体的危害]; R181.3 [流行病学各论];

学科分类号：

083001 [环境科学]; 100401 [流行病与卫生统计学];

摘要：

目的了解大气颗粒物(PM10、PM2.5)短期暴露对人群心脑血管疾病死亡的影响,获取大气颗粒物污染对人群心脑血管疾病死亡急性效应的暴露-反应关系。方法通过计算机联机检索及手工检索的方法收集1990年1月1日至2012年6月30日间公开发表的符合纳入标准的文献29篇,提取暴露-反应系数,采用Stata 12.0软件进行异质性分析、发表偏倚的检验及校正,利用固定效应或随机效应模型合并效应值。结果校正发表偏倚后,大气中PM10每升高10μg/m3,人群心脑血管疾病死亡的风险增加0.29%(95%CI:0.18%～0.49%);PM2.5每升高10μg/m3,心脑血管疾病死亡风险增加0.68%(95%CI:0.35%～1.02%),未发现明显的发表偏倚。亚组分析显示,亚洲人群PM10与PM2.5对心脑血管疾病急性死亡的暴露-反应关系效应估计值低于欧美地区;病例交叉设计得到的暴露-反应关系效应估计值高于时间序列分析。结论大气中PM10、PM2.5浓度的上升会导致人群心脑血管疾病死亡率增加,其中PM2.5导致的心脑血管疾病死亡风险更高。

引用

收藏

页码：417 / 421

页数：5

相关论文

共 20 条

[1]

大气污染对城市居民的健康效应及经济损失研究 [D].

赵越 .

中国地质大学（北京）,

2007

[2]

Fine Particulate Matter Constituents and Cardiopulmonary Mortality in a Heavily Polluted Chinese City [J].

Cao, Junji ;

Xu, Hongmei ;

Xu, Qun ;

Chen, Bingheng ;

Kan, Haidong .

ENVIRONMENTAL HEALTH PERSPECTIVES, 2012, 120 (03) :373-378

[3]

The Effects of Particulate Matter Sources on Daily Mortality: A Case-Crossover Study of Barcelona, Spain [J].

Ostro, Bart ;

Tobias, Aurelio ;

Cluerol, Xavier ;

Alastuey, Andres ;

Amato, Fulvio ;

Pey, Jorge ;

Perez, Noemi ;

Sunyer, Jordi .

ENVIRONMENTAL HEALTH PERSPECTIVES, 2011, 119 (12) :1781-1787

[4]

Fine particulate air pollution and daily mortality in Shenyang, China [J].

Ma, Yanjun ;

Chen, Renjie ;

Pan, Guowei ;

Xu, Xiaohui ;

Song, Weimin ;

Chen, Bingheng ;

Kan, Haidong .

SCIENCE OF THE TOTAL ENVIRONMENT, 2011, 409 (13) :2473-2477

[5]

Study on the Association between Ambient Air Pollution and Daily Cardiovascular and Respiratory Mortality in an Urban District of Beijing [J].

Zhang, Fengying ;

Li, Liping ;

Krafft, Thomas ;

Lv, Jinmei ;

Wang, Wuyi ;

Pei, Desheng .

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2011, 8 (06) :2109-2123

[6]

Short-term effect of fine particulate matter (PM2.5) on daily mortality due to diseases of the circulatory system in Madrid (Spain) [J].

Mate, T. ;

Guaita, R. ;

Pichiule, M. ;

Linares, C. ;

Diaz, J. .

SCIENCE OF THE TOTAL ENVIRONMENT, 2010, 408 (23) :5750-5757

[7]

Ambient air pollution and daily mortality in Anshan, China A time-stratified case-crossover analysis [J].

Chen, Renjie ;

Pan, Guowei ;

Kan, Haidong ;

Tan, Jianguo ;

Song, Weimin ;

Wu, Zhenyu ;

Xu, Xiaohui ;

Xu, Qun ;

Jiang, Cheng ;

Chen, Bingheng .

SCIENCE OF THE TOTAL ENVIRONMENT, 2010, 408 (24) :6086-6091

[8]

Estimating Mortality Effects of Fine Particulate Matter in Japan: A Comparison of Time-Series and Case-Crossover Analyses [J].

Ueda, Kayo ;

Nitta, Hiroshi ;

Ono, Masaji ;

Takeuchi, Ayano .

JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION, 2009, 59 (10) :1212-1218

[9]

Public Health and Air Pollution in Asia (PAPA): A multicity study of short-term effects of air pollution on mortality [J].

Wong, Chit-Ming ;

Vichit-Vadakan, Nuntavarn ;

Kan, Haidong ;

Qian, Zhengmin .

ENVIRONMENTAL HEALTH PERSPECTIVES, 2008, 116 (09) :1195-1202

[10]

Association of daily cause-specific mortality with ambient particle air pollution in Wuhan, China [J].

Qian, Zhengmin ;

He, Qingci ;

Lin, Hung-Mo ;

Kong, Lingli ;

Liao, Duanping ;

Dan, Jijun ;

Bentley, Christy M. ;

Wang, Beiwei .

ENVIRONMENTAL RESEARCH, 2007, 105 (03) :380-389