肠道菌群与抑郁症相关性的研究进展

被引：33

作者：

俞秋阳

左晗憬

嵇如月

郭玉洁

姜海瀛

李明成

机构：

[1] 北华大学医学检验学院

来源：

中国微生态学杂志 | 2018年 / 30卷 / 03期

关键词：

肠道菌群; 抑郁症; 益生菌;

D O I：

暂无

中图分类号：

R749.4 [情感性精神病];

学科分类号：

100204 [神经病学];

摘要：

正常人体内的肠道菌群数量可达100万亿,可参与人体的多项生理活动,包括营养物质的吸收与代谢、免疫系统的发育与成熟、抵挡外来病原体的入侵等,对人类的健康有着至关重要的作用。近年来发现肠道中的定植微生物与抑郁症、自闭症、焦虑症和帕金森病等一系列的神经精神疾病密切相关。最新研究表明,肠道菌群是通过神经、体液、代谢和免疫多种途径双向调节肠道和中枢神经系统的。目前,随着医学技术和医学理论的的提高,抑郁症与肠道菌群间的关系受到极大地重视。本文从肠道菌群对抑郁症的影响机制以及益生菌对抑郁症的改善作用两方面来综述肠道菌群与抑郁症相关性的最新进展。

引用

页码：358 / 361+373 +373

页数：5

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