干酪乳杆菌作为口服疫苗递呈抗原载体的可行性

被引:2
作者
徐义刚
赵丽丽
李一经
机构
[1] 东北农业大学
关键词
干酪乳杆菌; 口服疫苗; 抗原载体; 可行性;
D O I
10.13759/j.cnki.dlxb.2007.06.019
中图分类号
Q78 [基因工程(遗传工程)];
学科分类号
071007 ; 0836 ; 090102 ;
摘要
通过口服干酪乳杆菌安全性、胃液及胆汁酸耐受能力、肠道定植能力及外源基因在干酪乳杆菌中的遗传稳定性等实验,对干酪乳杆菌作为递呈疫苗抗原活菌载体的可行性进行了研究。结果表明:干酪乳杆菌符合益生菌的标准,可作为递呈疫苗抗原活菌载体。
引用
收藏
页码:54 / 55+80 +80
页数:3
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