Objective To compare the analgesic effect of patient-controlled epidural analgesia （PCEA） with multi-model analgesia for interventional uterine artery embolization （UAE）. Methods Five hundreds and forty ASA I-II patients receiving UAE were divided into 2 groups, group A: 284 patients received PCEA until 24 h postoperatively;Group B: 256 patients received PCEA for 12 h16 h after UAE procedure, then followed with oral NSAIDs or intramuscular injection of analgesic and so on for pain relief. VAS was recorded. Results In group A, the degree of pain decreased obviously after 12 h, PCA bolus frequency reduced markedly, and the ration of total/actual bolus frequency（D1/D2）was <2. There was no significant difference in VAS between two groups 17 h24 h after UAE procedure （P>0.05）. In group A , the mean time of ambulation and urinary catheters retaining were （25.9±6.9） h and （23.9±2.3） h respectively, however, in group B the mean times were （15.1±4.6） h and （14.6±2.5） h accordingly （P<0.05）. The Bruggman comfort score （BCS） of two groups were （6.1±2.3） and （7.6±1.9） in 24th hour postoperatively （P>0.05）. Conclusion PCEA can provide pain relief effectively during and after UAE procedure, and adjunctive multi-model analgesia may be more benefit to early activity.
