过敏性紫癜发病机制研究进展

被引:24
作者
蔡洁
胡波
机构
[1] 安徽医科大学第一附属医院儿科
关键词
过敏性紫癜; 肾炎; 免疫损伤; 基因;
D O I
暂无
中图分类号
R725.5 [小儿血液及淋巴系疾病];
学科分类号
摘要
过敏性紫癜(HSP)是小儿最常见的毛细血管变态反应性疾病之一,其发病机制目前尚未完全阐明。研究显示,体液免疫异常是HSP发病的主要机制,尤其是IgA的作用;T细胞功能改变、细胞因子和炎症介质的参与、易感基因等因素在其发病中也起着重要作用。HSP的发病与多种因素相关,因此从免疫学、遗传学等多方面分析有助于深化对HSP发病机制的认识。
引用
收藏
页码:39 / 41
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