急性期脑梗死磁共振波谱成像初步研究

被引：8

作者：

胡卫东 ^{[1
]}

项立 ^{[2
]}

王秀荣 ^{[1
]}

范义 ^{[1
]}

申云霞 ^{[1
]}

机构：

[1] 深圳市龙岗中心医院介入影像科

[2] 深圳市龙岗中心医院内二科

来源：

中华脑血管病杂志(电子版) | 2011年 / 5卷 / 01期

关键词：

急性脑梗死; 磁共振成像; 氢质子磁共振波谱成像;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

摘要：

目的分析评估急性脑梗死代谢物氢质子磁共振波谱成像(1HMRS)的临床应用价值。方法对32例急性期脑梗死患者进行常规核磁共振(MRI)及1HMRS扫描,梗死区N-乙酰天门冬氨酸(NAA),肌酸(Cr),胆碱化合物(Cho)与对侧相应正常脑区代谢产物比值(rNAA、rCr、rCho)及同侧乳酸/胆碱值(Lac/Cho),比较不同部位各代谢产物相对浓度。结果 rCr(F=6.102,P=0.085)各区域间无显著差异;rCho(F=2.229,P=0.094)各区域间无显著差异;rNAA中央部与外侧缘间有显著差异(F=2711.140,P<0.05);Lac/Cho区域各组间均有显著差异(F=29127.575,P=0.000)。结论 1HMRS检查对急性期脑梗死的诊断价值明显高于常规MRI,可同时检测脑梗死的进展情况。作为一种无创伤活体显示组织代谢的影像学方法1HMRS具有广阔的应用前景。

引用

页码：22 / 26

页数：5

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