抗核抗体和特异性自身抗体检测的临床应用

被引:18
作者
仇宁
机构
[1] 中国医学科学院、中国协和医科大学皮肤病研究所
关键词
抗核抗体; 特异性自身抗体; 结缔组织病;
D O I
暂无
中图分类号
R446.62 [免疫物质测定];
学科分类号
摘要
结缔组织病是一组多种临床症状重叠的自身免疫性疾病 ,抗核抗体和特异性自身抗体检测在结缔组织病诊断中起重要作用。现就临床上如何正确选择检查项目 ,正确使用实验结果诊断疾病、监测病程和判断预后等作一综述。
引用
收藏
页码:229 / 232
页数:4
相关论文
共 16 条
  • [1] The precipitating antibody to an acitic nuclear protein antigen, the Jo-1, in connective tissue disease.A marker for a subset of polymyositis with interstitial pulmonary fibrosis. Yoshida S,Akizuki M,Mimori T,et al. Arthritis and Rheumatism . 1983
  • [2] The clinical significance of autoantibody profiles in patients with SLE. Thompson D,Juby A,Davis P. Lupus . 1993
  • [3] Clinical significance of anti-RNP and anti-Sm autoantibodies as determined by immunoblotting and immunoprecipitation in sera from patients with connective tissue disease. Combe B,Rucheton M,Graafland H,et al. Clinical and Experimental Immunology . 1989
  • [4] Significance of the anti-Ro(SS-A) antibody in evaluation of patients with cutaneous manifestations of a connective tissue disease. Provost TT,Watson R,Simmons-O′Brien E. Journal of the American Academy of Dermatology . 1996
  • [5] Antinuclear antibody determinations in Ro ( SS-A)-positive, antinuclear antibody-negative lupus and Sjogron′s syndrome patients. Dore N,Synkowski D,Provost TT. Journal of the American Academy of Dermatology . 1983
  • [6] Scl-70 antibodies: a specific marker of systemic sclerosis. Jarzabek-Chorzelska M,Blaszczyk M,Jablonska S,et al. Br J Dermatol . 1986
  • [7] Guidelines for clinical use of the antinuclear antibody test and tests for specific autoantibodies to nuclear antigens. Kavanaugh A,Tomar R,Reveille J,et al. Archives of Pathology and Laboratory Medicine . 2000
  • [8] Immunoe responses to SS-A 52-kDa and 60-kDa proteins and to SS-B 50-kDa protein in mothers of infants with neonatal lupus erythematosus. Yukiko N. Br J Dermatol . 2000
  • [9] Serologic markers of disease activity in SLE. Sprionk PE,Limburg PC,Kallenberg GM. Lupus . 1995
  • [10] Utilization and predictive value of laboratory tests in patients referred to rheumatologists by primary care physicians. Suarez-Almazor ME,Gonzalez-Lopez L,Gamez-Nava JI,et al. The Journal of Rheumatology . 1998