血清及尿中Kim-1及CysC联合监测对急性肾衰竭的诊断意义

被引:5
作者
陈朴 [1 ]
张立营 [1 ]
高鹏 [1 ]
彭宇生 [1 ]
王鹏 [1 ]
张鹤轩 [2 ]
机构
[1] 宜宾市第一人民医院检验科
[2] 泸州医学院附属医院检验科
关键词
尿肾损伤分子-1; 血清胱抑素C; 急性肾衰竭;
D O I
10.13241/j.cnki.pmb.2016.22.045
中图分类号
R692.5 [肾功能衰竭];
学科分类号
摘要
目的:探讨血清及尿中Kim-1及CysC联合监测在临床诊断急性肾衰竭中的意义及价值。方法:选取我院重症监护病房的泌尿系统疾病患者108例根据急性肾衰竭诊断标准将其分为两组:58例符合急性肾衰竭诊断标准为ARF组,50例非急性肾衰竭为非ARF组,另取正常体检的健康人5 0例为正常对照组,检测三组患者的血清肌酐浓度、血清尿素氮、血清和尿KIM-1及Cys-C浓度,进而对血清和尿KIM-1及Cys-C水平进行分析。结果:与对照组和非ARF组相比,ARF组血清肌酐浓度、血清尿素氮、血清和尿KIM-1及Cys-C水平较高(P<0.05)。与血清和尿KIM-1及Cys-C水平的单独检测相比,两者联合检测敏感性以及特异性较高(P<0.05)。结论:血清及尿中Kim-1及CysC水平升高可作为急性肾衰竭的评估指标,两者联合监测对急性肾衰竭患者的诊断具有重要意义,对疾病预后有重要指导价值。
引用
收藏
页码:4370 / 4372+4376 +4376
页数:4
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