脊髓损伤的干细胞治疗研究进展

被引：5

作者：

吴月奎 ^{[1
]}

王尚武 ^{[1
]}

戴宜武 ^{[2
]}

徐如祥 ^{[2
]}

机构：

[1] 首都医科大学附属密云教学医院神经外科

[2] 北京军区总医院附属八一脑科医院

来源：

中华神经医学杂志 | 2014年 / 13卷 / 07期

关键词：

脊髓损伤; 干细胞; 移植;

D O I：

暂无

中图分类号：

R651.2 [脊髓];

学科分类号：

100223 [神经外科学];

摘要：

<正>脊髓损伤是临床上常见的中枢神经系统的严重创伤,可造成运动、感觉障碍及自主神经功能紊乱,高位损伤者甚至影响呼吸循环功能,具有极高的致残率和致死率,给患者及家属带来严重的经济和精神负担,也造成了巨大的社会压力。外伤是脊髓损伤最常见的原因,常由交通事故、坠落及暴力打伤引起,其他常见的原因有肿瘤压迫、感染、医源性损伤等[1-2]。脊髓损伤预后较差,一方面由于神经元再生能力较差;另一方面,脊髓损伤后,局部神经元坏死、凋亡,胶质瘢痕形成,阻碍了神经网络的重构,且损伤微环境中存在多种抑制

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