肺炎衣原体感染及C反应蛋白与冠脉病变程度的关系

被引:5
作者
刘启明
周胜华
祁述善
沈向前
李旭平
张志辉
机构
[1] 中南大学湘雅二医院心内科
[2] 中南大学湘雅二医院心内科 长沙市
[3] 长沙市
关键词
冠状动脉疾病; 肺炎衣原体; 抗体; C反应蛋白;
D O I
暂无
中图分类号
R543.3 [冠状动、静脉疾病];
学科分类号
1002 ; 100201 ;
摘要
目的 :探讨肺炎衣原体抗体IgA (Chlamydiapneumoniaeantibody IgA ,Cpn IgA)及高敏性C反应蛋白(highsensitiveC reactiveprotein ,hs CRP)与冠脉病变程度之间的关系。方法 :用酶联免疫吸附试验 (enzymelinkedimmuneadsorptionassay ,ELISA)和超敏免疫透射比浊法分别测定 85例经冠脉造影证实冠脉病变患者和 2 5例正常对照组的血清Cpn IgA和hs CRP水平 ,比较它们在不同程度冠状动脉病变之间的关系。结果 :(1)冠脉病变患者血清Cpn IgA感染率和hs CRP水平明显高于对照组 ;(2 )多支冠脉病变者血清Cpn IgA水平明显高于单支病变者 ;(3 )冠脉病变患者血清Cpn IgA与hs CRP水平之间成正相关 (r =0 3 12 ,P <0 0 1)。结论 :血清Cpn IgA水平与冠状动脉粥样硬化程度相关 ,Cpn感染导致冠状动脉粥样硬化过程中 ,炎症反应发挥介导作用
引用
收藏
页码:854 / 855
页数:2
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