骨质疏松与骨性关节炎关系的研究进展

被引:17
作者
伦学刚
谈志龙
白人骁
机构
[1] 天津医院骨科研究所
关键词
骨质疏松; 骨关节炎; 综述文献;
D O I
暂无
中图分类号
R580 []; R684 [关节疾病及损伤];
学科分类号
100220 [骨科学];
摘要
骨质疏松(osteoporosis,OP)与骨关节炎(osteoarthritis,OA)是临床常见病多发病,骨质疏松症是以骨量减少、骨组织微细结构破坏导致骨骼脆性和骨折危险性增加为特征的一种系统性全身性骨骼疾病。而骨性关节炎是以软骨改变为主要特征,进而造成软骨下骨坏死,囊性变,骨密度增加和伴发骨赘形成的一种非特异性炎症。骨质疏松在骨关节炎发病过程中到底扮演什么角色,是否为骨关节炎的病因之一,国内外有大量文献对此进行了报道,其观点也不甚一致,目前存在3种:①OA与OP正相关,OP是OA的病因之一;②OA与OP负相关,OP不是OA的病因;③OA与OP不相关。通过查阅文献,笔者认为OP与OA不相关的可能性不大。本文就两者之间的正负关系作一综述,以期能对以后的临床工作有一定的指导作用。
引用
收藏
页码:876 / 878
页数:3
相关论文
共 12 条
[1]
Cancellous bone changes in hip osteoarthritis: a short-term longitudinal study using fractal signature analysis [J].
Papaloucas, CD ;
Ward, RJ ;
Tonkin, CJ ;
Buckland-Wright, C .
OSTEOARTHRITIS AND CARTILAGE, 2005, 13 (11) :998-1003
[2]
Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits [J].
Castañeda, S ;
Largo, R ;
Calvo, E ;
Rodríguez-Salvanés, F ;
Marcos, ME ;
Díaz-Curiel, M ;
Herrero-Beaumont, G .
SKELETAL RADIOLOGY, 2006, 35 (01) :34-41
[3]
Bone mineral density and vertebral fracture history are associated with incident and progressive radiographic knee osteoarthritis in elderly men and women: The Rotterdam Study [J].
Bergink, AP ;
Uitterlinden, AG ;
Van Leeuwen, JPTM ;
Hofman, A ;
Verhaar, JAN ;
Pols, HAP .
BONE, 2005, 37 (04) :446-456
[4]
Expression of ICAM-1 by osteoblasts in healthy individuals and in patients suffering from osteoarthritis and osteoporosis [J].
Lavigne, P ;
Benderdour, M ;
Lajeunesse, D ;
Shi, Q ;
Fernandes, JC .
BONE, 2004, 35 (02) :463-470
[5]
Changes in articular cartilage and subchondral bone histomorphometry in osteoarthritic knee joints in humans [J].
Bobinac, D ;
Spanjol, J ;
Zoricic, S ;
Maric, I .
BONE, 2003, 32 (03) :284-290
[6]
Subchondral tibial bone mineral density predicts future joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis [J].
Bruyere, O ;
Dardenne, C ;
Lejeune, E ;
Zegels, B ;
Pahaut, A ;
Richy, F ;
Seidel, L ;
Ethgen, O ;
Henrotin, Y ;
Reginster, JY .
BONE, 2003, 32 (05) :541-545
[7]
Altered bone mineral metabolism in patients with osteoarthritis [J].
El Miedany, YM ;
Mehanna, AN ;
El Baddini, MA .
JOINT BONE SPINE, 2000, 67 (06) :521-527
[8]
Early morphometric and anisotropic change in periarticular cancellous bone in a model of experimental knee osteoarthritis quantified using microcomputed tomography [J].
Boyd, SK ;
Müller, R ;
Matyas, JR ;
Wohl, GR ;
Zernicke, RF .
CLINICAL BIOMECHANICS, 2000, 15 (08) :624-631
[9]
骨质疏松症与骨关节病 [J].
贾龙 ;
付丽明 ;
范锦勤 .
韶关学院学报(自然科学版), 2005, (03) :112-115
[10]
骨性关节炎的定量超声骨密度研究 [J].
黄火高 ;
郑毅 ;
尹义存 .
天津医药, 2004, (12) :737-739