华法林在心房颤动抗凝治疗中的应用

被引:34
作者
何华
马长生
机构
[1] 首都医科大学附属北京安贞医院心内科
关键词
华法林; 心房颤动; 抗凝治疗;
D O I
暂无
中图分类号
R541.75 [];
学科分类号
摘要
心房颤动(AF)是最常见的持续性心律失常,其主要可能致命的危险就是血栓形成。华法林抗凝治疗可显著减少2/3卒中风险,对瓣膜病和非瓣膜病AF均有效,但存在监测较麻烦、治疗窗窄、有潜在出血危险等不利之处。本文比较了华法林临床应用与其他口服凝血酶抑制剂和Xa因子拮抗剂及抗血小板药物治疗的现状。
引用
收藏
页码:16 / 19
页数:4
相关论文
共 5 条
  • [1] Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial
    Connolly, S.
    Pogue, J.
    Hart, R.
    Pfeffer, M.
    Hohnloser, S.
    Chrolavicius, S.
    Yusuf, S.
    [J]. LANCET, 2006, 367 (9526) : 1903 - 1912
  • [2] Culprit factors for the failure of well-conducted warfarin therapy to prevent ischemic events in patients with atrial fibrillation - The role of homocysteine
    Poli, D
    Antonucci, E
    Cecchi, E
    Marcucci, R
    Liotta, AA
    Cellai, AP
    Lenti, M
    Gensini, GF
    Abbate, R
    Prisco, D
    [J]. STROKE, 2005, 36 (10) : 2159 - 2163
  • [3] Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation - The AnTicoagulation and risk factors in atrial fibrillation (ATRIA) study
    Fang, MC
    Singer, DE
    Chang, YC
    Hylek, EM
    Henault, LE
    Jensvold, NG
    Go, AS
    [J]. CIRCULATION, 2005, 112 (12) : 1687 - 1691
  • [4] Antithrombotic therapy for stroke prevention in atrial fibrillation
    Go, AS
    Fang, MC
    Singer, DE
    [J]. PROGRESS IN CARDIOVASCULAR DISEASES, 2005, 48 (02) : 108 - 124
  • [5] Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial
    Albers, GW
    Diener, HC
    Grind, M
    Halperin, JL
    Horrow, J
    Olsson, SB
    Petersen, P
    Vahanian, A
    Frison, L
    Nevinson, M
    Partridge, S
    [J]. LANCET, 2003, 362 (9397) : 1691 - 1698