F-FDG PET-CT确定非小细胞肺癌淋巴结放疗靶区的初步探讨

被引:11
作者
刘兰平
于金明
郭洪波
付政
韩安勤
杨国仁
机构
[1] 山东省肿瘤医院放疗科
[2] 山东省肿瘤医院胸外科
[3] 山东省肿瘤医院PET-CT中心
关键词
18F-FDG PET—CT; 非小细胞肺癌; 淋巴结放疗靶区;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100214 ;
摘要
目的探讨18F-FDG PET-CT确定非小细胞肺癌(NSCLC)患者区域淋巴结放疗靶区的价值。方法回顾性分析58例经根治性手术治疗的NSCLC患者,术前同期行PET-CT和CT检查。经盲法阅片后,由肿瘤放射治疗医师结合影像诊断结果分别在PET-CT和CT图像上勾画靶区,并与病理诊断结果进行对照。结果CT诊断纵隔淋巴结转移的灵敏度、特异度、准确率、阳性预测值及阴性预测值分别为56.0%、54.2%、54.8%、38.9%和70.3%,PET-CT分别为88.0%、85.4%、86.3%、75.9%和93.2%,两者差异均有统计学意义(P<0.05)。CT和PET-CT对诊断肺门区域淋巴结的差异无统计学意义。18F-FDG PET参与靶区勾画后,46.5%的患者淋巴结靶区改变,其靶区完全包含转移性淋巴结的准确率为75.9%,与单纯CT(48.3%)的准确率比较,差异有统计学意义(P<0.05)。结论18F-FDG PET-CT能更准确地估计NSCLC患者区域淋巴结转移的范围,从而指导放疗靶区的勾画。
引用
收藏
页码:453 / 456
页数:4
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