表观弥散系数对确定急性缺血性卒中缺血半暗带的潜在价值

被引:18
作者
马丽 [1 ]
高培毅 [1 ]
胡庆茂 [2 ]
林燕 [1 ]
薛静 [1 ]
荆利娜 [1 ]
王效春 [1 ]
陈志军 [2 ]
王伊龙 [3 ]
廖晓凌 [3 ]
机构
[1] 首都医科大学附属北京天坛医院神经影像中心
[2] 中国科学院香港中文大学深圳先进集成技术研究所,中国科学院深圳先进技术研究院,中国科学院医学信息与健康工程学重点实验室
[3] 首都医科大学附属北京天坛医院神经内科
基金
国家科技攻关计划;
关键词
脑梗死; 磁共振成像; 诊断显像;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
摘要
目的探讨表观弥散系数(apparent diffusion coefficient,ADC)对确定急性缺血性卒中缺血半暗带的潜在价值。方法选择发病9h内完成多模式磁共振成像(magnetic resonance imaging,MRI)检查的前循环急性缺血性卒中患者49例。应用自制软件进行灌注加权像(perfusion-weighted imaging,PWI)和弥散加权像(diffusion-weighted imaging,DWI)异常区域的体积测量。缺血半暗带以PWI/DWI错配表示。同时采用全自动图像分析系统,以DWI图像计算得到的ADC图作为输入数据,来判断缺血半暗带的存在(以下简称为ADC方法),然后比较这两种方法在判断缺血半暗带方面的差异。结果入选的49例患者中,存在PWI/DWI错配者为43例,符合ADC方法判断缺血半暗带标准者有41例。这两种方法在判断是否存在缺血半暗带的结果中有41例相符,对判断缺血半暗带的差异无统计学意义(P>0.05)。ADC方法判断缺血半暗带的敏感度为88.4%、特异度为50.0%。结论由于不需做PWI检查,ADC方法对确定缺血半暗带具有潜在的临床实用价值,有可能成为一种简便易行的确定缺血半暗带的方法。
引用
收藏
页码:730 / 736
页数:7
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