Cys C与NT-proBNP对急性心衰患者病情和预后评估

被引：13

作者：

蔡凤信

机构：

[1] 滦平县中医院心内科

来源：

临床军医杂志 | 2016年 / 44卷 / 07期

关键词：

急性心力衰竭; N末端脑钠肽前体; 半胱氨酸蛋白酶抑制剂C; 预后;

D O I：

10.16680/j.1671-3826.2016.07.24

中图分类号：

R541.6 [血液循环衰竭];

学科分类号：

100201 [内科学];

摘要：

目的探讨血浆半胱氨酸蛋白酶抑制剂C(Cys C)和N末端脑钠肽前体(NT-proBNP)对急性心力衰竭患者病情和预后的评估作用。方法选取滦平县中医院自2013年1月至2014年6月急诊心衰患者115例设为观察组,选取我院同期的健康体检者58例作为对照组,所有研究对象均行血浆NT-proBNP和Cys C含量检测,比较两组研究对象NT-proBNP和Cys C含量的区别。观察组患者根据预后分为事件组(n=51)及非事件组(n=64),分别比较两组NT-proBNP和Cys C含量的区别;心衰患者根据临床心功能情况分成Ⅱ级36例,Ⅲ级39例和Ⅳ级40例,分别比较NT-proBNP和Cys C与心衰严重程度的相关性。结果观察组NT-proBNP和Cys C含量均高于对照组(P<0.01);心衰患者中,事件组NT-proBNP和Cys C含量均高于非事件组(P<0.05)。NT-proBNP(r=0.359)和Cys C含量(r=0.426)与心衰严重程度呈正相关(P<0.01)。结论NT-proBNP和Cys C水平能够评估急性心衰患者病情和预后,NT-proBNP和Cys C水平越高,病情越重,预后越差。

引用

页码：743 / 744

页数：2

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