浙江蝮蛇蛇毒对鹌鹑动脉粥样硬化的影响

被引:5
作者
孙黎光
郝文学
Jason C H shih
机构
[1] 中国医科大学基础医学部生化教研室
[2] 中国医科大学老年病研究中心
[3] 美国北卡州立大学生物技术实验室
关键词
蛇毒; 动脉粥样硬化; 血清胆固醇; 凝血时间;
D O I
暂无
中图分类号
学科分类号
摘要
用DEAE-cellulose DE-52柱层析分离浙江蝮蛇蛇毒,用其中一组份给已经发生动脉粥样硬化的鹌鹑做静脉注射(隔日1次)。7周后发现此组份可使血清胆固醇含量下降,凝血时间延长,并降低肝脂肪化程度。此组份含二种主要蛋白,分子量为63000和51000,后者有精氨酸酯酶活性,二者均有纤溶酶活性。
引用
收藏
页码:326 / 330
页数:5
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