膝骨关节炎动物模型研究进展

被引：30

作者：

李军 ^{[1
]}

彭峥 ^{[1
]}

刘兆丰 ^{[1
]}

胥方元 ^{[2
]}

机构：

[1] 泸州市人民医院

[2] 西南医科大学附属医院

来源：

西部医学 | 2019年 / 31卷 / 12期

关键词：

膝骨关节炎; 动物模型; 动物选择; 研究进展;

D O I：

暂无

中图分类号：

R684.3 [关节炎]; R-332 [医用实验动物学];

学科分类号：

100220 [骨科学]; 100402 [劳动卫生与环境卫生学];

摘要：

膝骨关节炎具有高发病率及高致残率等特征,现阶段对其发病机制尚不完全清楚,亦缺乏真正有效的治愈方法,目前对其发病机制及治疗的研究仍以动物实验为主,其关键是建立理想的动物模型。目前用于膝骨关节炎研究的实验动物多种,造模方式多样,且各具优缺点。在进行动物实验前,应结合研究目的、模型特点综合考虑。本文就近年来膝骨关节炎动物模型的研究进展作一综述。

引用

页码：1962 / 1965+1981 +1981

页数：5

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