Wnt信号通路与子宫肌瘤相关性研究进展

被引:7
作者
史杨 [1 ]
赵莉 [2 ]
曹阳 [2 ]
周洁云 [3 ]
杨英 [2 ]
张婷婷 [2 ]
机构
[1] 上海中医药大学
[2] 上海市岳阳中西医结合岳阳医院妇科
[3] 上海市计划生育研究所
关键词
蛋白质类; 信号传导; 子宫肿瘤; 肌瘤;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
Wnt信号通路是调节细胞发育和生长的一个关键途径,在正常情况下对胚胎发育和成人部分组织的形成和功能发挥起着重要作用。其异常激活则参与了人类多种肿瘤的发病过程,目前研究表明,Wnt通路中的多种因子与子宫肌瘤的发生发展有关,通过影响细胞凋亡、血管生成等发挥作用,并可与多种生长因子相互影响。但某些Wnt分子在子宫肌瘤中的表达尚存一定的争议。就Wnt信号通路与子宫肌瘤关系的研究进展进行简要综述。
引用
收藏
页码:137 / 140
页数:4
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