作用于微管的天然产物

被引：11

作者：

崔萍

霍长虹

李力更

张嫚丽

史清文

机构：

[1] 河北医科大学药学院天然药物化学教研室

来源：

中草药 | 2010年 / 41卷 / 01期

关键词：

微管; 微管蛋白; 天然产物;

D O I：

暂无

中图分类号：

R284 [中药化学];

学科分类号：

1008 ;

摘要：

微管在有丝分裂中扮演着重要的角色,微管靶点药物是抗肿瘤药物的重要组成部分。很多天然产物能作用于微管的不同部位,其中包括紫杉醇类和长春花碱类。根据这些天然产物对微管蛋白聚合所起的促进作用或抑制作用,将其划分成两类,着重讨论它们的来源、作用机制和生物活性。

引用

页码：139 / 147

页数：9

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