中药药对配伍机制的现代研究

被引：66

作者：

宋佳 ^{[1
,2
]}

高晓霞 ^{[1
]}

田俊生 ^{[1
]}

秦雪梅 ^{[1
]}

杜冠华 ^{[1
,3
]}

周玉枝 ^{[1
]}

机构：

[1] 山西大学中医药现代研究中心

[2] 山西大学化学化工学院

[3] 中国医学科学院北京协和医学院药物研究所

来源：

中草药 | 2017年 / 48卷 / 21期

关键词：

药对; 配伍机制; 物质基础; 药动学; 中药新药研发;

D O I：

暂无

中图分类号：

R289 [方剂学];

学科分类号：

100504 ;

摘要：

药对作为中药配伍的基本形式,是沟通单味药与复方的重要桥梁,研究药对的配伍机制对揭示复方配伍的科学内涵具有重要意义。目前,许多研究者从药对配伍前后的化学成分、药动学及药理作用差异着手对药对配伍机制展开研究。通过查阅文献,归纳总结药对配伍机制的研究现状,并提出展望,以期为药对及复方配伍机制的进一步深入研究及以药对为基础的中药新药开发奠定基础。

引用

页码：4367 / 4374

页数：8

共 41 条

[1]

枳实—白芍药对干预肝郁脾虚型IBS大鼠的配伍及药动学研究.[D].陈稚.广州中医药大学.2014, 01

[2]

麻黄—白术药对主要化学成分、药效及尿液代谢物研究.[D].邢学锋.南方医科大学.2013, 04

[3]

麻黄类药对组成规律的基础研究.[D].朱钊铭.南方医科大学.2014, 01

[4]

双丹方中丹参对丹皮药代动力学影响研究.[D].刘春芝.西北大学.2009, 08

[5]

The comparative pharmacokinetics of four bioactive ingredients after administration of Ramulus Cinnamomi–Radix Glycyrrhizae herb pair extract; Ramulus Cinnamomi extract and Radix Glycyrrhizae extract.[J].Shengnan Wang;Lijiao Sun;Liqiang Gu;Yuanyuan Zhang;Simin Zhao;Long‐shan Zhao;Kai‐shun Bi;Xiaohui Chen.Biomedical Chromatography.2016, 8

[6]

Concurrent quantification and comparative pharmacokinetic analysis of bioactive compounds in the Herba Ephedrae-Semen Armeniacae Amarum herb pair.[J].Shuai Song;Feilong Chen;Xuefeng Xing;Mengyue Ren;Qinhai Ma;Ying Xie;Qingfa Tang;Jiabo Luo.Journal of Pharmaceutical and Biomedical Analysis.2015,

[7]

Comparative metabolomics analysis on invigorating blood circulation for herb pair Gui-Hong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach.[J].Shujiao Li;Hang Lin;Yuping Tang;Weixia Li;Juan Shen;Jun Kai;Shijun Yue;Guanxiong Shang;Zhenhua Zhu;Erxin Shang;Changbin Zhang;Li Zhang;Hui Yan;Pei Liu;Jin-ao Duan.Journal of Pharmaceutical and Biomedical Analysis.2015,

[8]

Quantitative evaluation main of the components in Paeoniae Radix Alba–Atractylodis Macrocephalae Rhizoma herbal pair by high‐performance liquid chromatography.[J].Xin Wu;Gang Cao;Qinglin Li;Baochang Cai;Siyi Hu.J. Sep. Science.2015, 2

[9]

Metabolomic approaches for orange origin discrimination by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.[J].Ramon Díaz;Oscar J. Pozo;Juan V. Sancho;Félix Hernández.Food Chemistry.2014,

[10]

Comparative metabolomics analysis on hematopoietic functions of herb pair Gui-Xiong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach.[J].Weixia Li;Yuping Tang;Jianming Guo;Erxin Shang;Yefei Qian;Linyan Wang;Li Zhang;Pei Liu;Shulan Su;Dawei Qian;Jin-ao Duan.Journal of Chromatography A.2014,

← 1 2 3 4 5 →