ω-3多元不饱和脂肪酸与动脉粥样硬化及其危险因素

被引：3

作者：

刘雨蒙

祖凌云

高炜

机构：

[1] 北京大学第三医院心内科,卫生部心血管分子生物学与调节肽重点实验室,分子心血管学教育部重点实验室,心血管受体研究北京市重点实验室

来源：

中国介入心脏病学杂志 | 2017年 / 25卷 / 05期

关键词：

ω-3多元不饱和脂肪酸; 动脉粥样硬化; 高血压; 高脂血症; 糖尿病;

D O I：

暂无

中图分类号：

R543.5 [动脉疾病];

学科分类号：

1002 ; 100201 ;

摘要：

<正>多元不饱和脂肪酸（polyunsaturated fatty acids,PUFAs）是人体生长的必需物质,与人体健康密切相关。PUFAs中第一个双键出现在甲基端碳原子的第3位的一大类称之为ω-3 PUFAs。ω-3 PUFAs是人体的必需脂肪酸,体内不能合成,主要由食物直接供给。早在1976年,学者们就发现,以海鱼、鲸类、海豹等海洋动物为主要食物来源的爱斯基摩人心肌梗死的发病率明显低于丹麦人[1]。近些年来,大量的临

引用

页码：296 / 300

页数：5

共 20 条

[1] Higher Oily Fish Consumption in Late Pregnancy Is Associated With Reduced Aortic Stiffness in the Child at Age 9 Years [J].

Bryant, Jennifer ;

Hanson, Mark ;

Peebles, Charles ;

Davies, Lucy ;

Inskip, Hazel ;

Robinson, Sian ;

Calder, Philip C. ;

Cooper, Cyrus ;

Godfrey, Keith M. .

CIRCULATION RESEARCH, 2015, 116 (07) :1202-+

[2]

Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis[J] . Michel Guichardant,Catherine Calzada,Nathalie Bernoud-Hubac,Michel Lagarde,Evelyne Véricel.BBA - Molecular and Cell Biology of Lipids . 2014

[3] Omega-3 PUFAs improved endothelial function and arterial stiffness with a parallel antiinflammatory effect in adults with metabolic syndrome [J].

Tousoulis, Dimitris ;

Plastiras, Aris ;

Siasos, Gerasimos ;

Oikonomou, Evangelos ;

Verveniotis, Aleksis ;

Kokkou, Eleni ;

Maniatis, Konstantinos ;

Gouliopoulos, Nikolaos ;

Miliou, Antigoni ;

Paraskevopoulos, Thodoris ;

Stefanadis, Christodoulos .

ATHEROSCLEROSIS, 2014, 232 (01) :10-16

[4]

The Effect of n-3 Fatty Acids on Glucose Homeostasis and Insulin Sensitivity[J] . Flachs,P,Rossmeisl,M,Kopecky,J.Physiological Research . 2014

[5]

Docosahexaenoic Acid Supplementation, Vascular Function and Risk Factors for Cardiovascular Disease: A Randomized Controlled Trial in Young Adults[J] . Atul Singhal,Julie Lanigan,Clare Storry,Sarah Low,Toni Birbara,Alan Lucas,John Deanfield.Journal of the American Heart Association . 2013 (4)

[6]

Effect of Fish Oil on Circulating Adiponectin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials[J] . Jason H. Y. Wu,Leah E. Cahill,Dariush Mozaffarian.The Journal of Clinical Endocrinology & Metabolism . 2013 (6)

[7] Constitutively Active TRPC Channels of Adipocytes Confer a Mechanism for Sensing Dietary Fatty Acids and Regulating Adiponectin [J].

Sukumar, Piruthivi ;

Sedo, Alicia ;

Li, Jing ;

Wilson, Lesley A. ;

O'Regan, David ;

Lippiat, Jonathan D. ;

Porter, Karen E. ;

Kearney, Mark T. ;

Ainscough, Justin F. X. ;

Beech, David J. .

CIRCULATION RESEARCH, 2012, 111 (02) :191-U170

[8]

Effect of omega-3 fatty acids supplementation on endothelial function: A meta-analysis of randomized controlled trials[J] . Qianqian Wang,Xiaohua Liang,Laiyuan Wang,Xiangfeng Lu,Jianfeng Huang,Jie Cao,Hongfan Li,Dongfeng Gu.Atherosclerosis . 2012 (2)

[9] Do long-chain n-3 fatty acids reduce arterial stiffness? A meta-analysis of randomised controlled trials [J].

Pase, Matthew P. ;

Grima, Natalie A. ;

Sarris, Jerome .

BRITISH JOURNAL OF NUTRITION, 2011, 106 (07) :974-980

[10]

Carotid intima-media thickness changes with Mediterranean diet: A randomized trial (PREDIMED-Navarra)[J] . Manuel Murie-Fernandez,Pablo Irimia,Estefanía Toledo,Eduardo Martínez-Vila,Pilar Buil-Cosiales,Manuel Serrano-Martínez,Valentina Ruiz-Gutiérrez,Emilio Ros,Ramon Estruch,Miguel ángel Martínez-González.Atherosclerosis . 2011 (1)

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