一种新的脂肪因子——Chemerin

被引：10

作者：

张燕华

曾龙驿

机构：

[1] 中山大学附属第三医院内分泌科

来源：

国际内科学杂志 | 2009年 / 36卷 / 04期

关键词：

Chemerin/TIG2; Chemerin受体; 脂肪因子;

D O I：

暂无

中图分类号：

R589.2 [脂肪代谢障碍]; R341 [];

学科分类号：

100201 [内科学];

摘要：

Chemerin是孤独G蛋白偶联受体chemerin R的内源性配体,在组织中分布广泛,具有调节先天性及获得性免疫反应,调节骨骼的发育和代谢,维持皮肤正常生理功能等多种生物学效应。最近的研究表明chemerin是一种脂肪因子,其表达水平与肥胖相关,并有调节脂肪细胞的分化、脂解,促进脂肪细胞内胰岛素信号传导途径等生物学效应。因此chemerin是一种重要的生理调节肽。

引用

收藏

页码：202 / 205

页数：4

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