水通道蛋白在外伤性脑水肿中的作用

被引:4
作者
张琳
袁芳
机构
[1] 首都医科大学
[2] 北京市神经外科研究所
关键词
水通道蛋白; 水通道蛋白4; 脑外伤; 脑水肿;
D O I
10.16636/j.cnki.jinn.2004.06.027
中图分类号
R651 [头部及神经外科学];
学科分类号
1002 ; 100210 ;
摘要
本文介绍了水通道蛋白(Aquaporin,AQP)的分类与分布以及 AQP4调节的最新研究结果。MAPKs 信号通路可能参与 AQP4的表达调节,alpha-syntrophin 可能参与 AQP4的定位调控。总结归纳了 AQP4在外伤性脑水肿中的作用,指出 AQP4可能起到促进外伤性脑水肿形成及消散的双重作用。
引用
收藏
页码:589 / 591
页数:3
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