细胞内炎症信号通路交汇作用研究进展

被引：43

作者：

刘辉

姚咏明

机构：

[1] 中国人民解放军第医院全军烧伤研究所基础部,中国人民解放军第医院全军烧伤研究所基础部北京,北京

来源：

中国病理生理杂志 | 2005年 / 08期

基金：

国家杰出青年科学基金;

关键词：

信号转导; 炎症; 有丝分裂素激活蛋白激酶类; NF-κB;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100104 ;

摘要：

Janus kinase-signal transduction and transcription activator (JAK-STAT), mitogen- activated protein kinase (MAPK) and nuclear factor κB (NF-κB) are three important cellular signalling pathways, which play pivotal roles in regulation of cellular physiologic as well as pathophysiologic functions. Based on the elucidation of the research progress of three signalling cascades, respectively, the current review focuses on the cross-talk of these signalling transduction, and the up-to-date details are also presented on their regulation in inflammatory response.

引用

页码：1607 / 1613+1627 +1627

页数：8