干扰素与骨质疏松关系的研究进展

被引：7

作者：

周隆

付勤

机构：

[1] 中国医科大学附属盛京医院脊柱关节骨科

来源：

中国骨质疏松杂志 | 2015年 / 21卷 / 11期

关键词：

干扰素; 骨质疏松; 骨免疫学;

D O I：

暂无

中图分类号：

R580 [];

学科分类号：

摘要：

近些年来骨骼系统与免疫系统的相互作用关系引起了人们的兴趣。作为免疫调节因子中的重要成员,干扰素同样对骨形成和骨吸收有着重大影响。目前发现与骨质疏松相关的干扰素主要包括IFN-α、IFN-β以及IFN-γ,本文对干扰素在骨质疏松形成过程中发挥的作用做了详细阐述,以期为骨质疏松症的防治提供新的思路。目前干扰素与骨质疏松关系的相关研究取得了较大的进步,在临床试验中,干扰素对部分继发骨质疏松症患者的治疗效果令人满意,想要把研究结果转化为临床仍是一条较漫长的道路。干扰素的应用仍存在很多问题,这些问题如果得到妥善解决,将有助于将干扰素顺利应用于临床,也必将促使骨质疏松的防治水平进一步提高。

引用

收藏

页码：1397 / 1401

页数：5

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