润滑素与骨性关节炎

被引：6

作者：

雷蕾 ^{[1
]}

周月珠 ^{[1
]}

倪国新 ^{[2
,3
]}

机构：

[1] 福建医科大学医学技术与工程学院

[2] 福建医科大学

[3] 南方医院创伤骨科

来源：

中国康复医学杂志 | 2013年 / 28卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

<正>关节软骨是一种非常有效的摩擦学系统,可在各种负荷(压力)和滑动速度中提供低摩擦以防止磨损[1]。关节的最佳功能依赖于软骨的最低摩擦系数环境的维持[2];有关关节软骨的润滑机制尚未完全清楚,其可能的机制包括:流体力学润滑、边界润滑、弹性变形、流体压力等[3]。虽然有关软骨润滑的摩擦学机制是多因素的,但在边界润滑体系中,机械负荷在接触表面的粗糙的固体-固体之间传导,该传导表面是由一个薄的润滑分子层分离[5]。润滑素(lubricin)作为软骨表

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页码：93 / 96

页数：4

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