多发性硬化相关T细胞免疫机制的研究进展

被引:22
作者
杨帆 [1 ]
顔光涛 [2 ]
李涛 [1 ]
机构
[1] 中国中医科学院西苑医院脑病科
[2] 中国人民解放军总医院基础所生化室
关键词
多发性硬化; T细胞; Th17细胞; 自身免疫;
D O I
暂无
中图分类号
R744.51 [];
学科分类号
摘要
多发性硬化是中枢神经系统常见的免疫炎症性脱髓鞘疾病,发病机制主要以T细胞介导的细胞免疫为主,特别是髓鞘特异性CD4、CD8 T细胞起着关键作用。随着国内外对免疫性疾病的研究逐渐深入,对T细胞各种亚型,如Th17、Treg、CD8 T细胞,以及它们在中枢神经系统中各自作用的特点有了新的认识。现将它们对中枢神经系统的炎症和损害的分子机制的研究综述如下。
引用
收藏
页码:452 / 456
页数:5
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