入院时血尿素水平与溶栓治疗的老年急性缺血性脑卒中患者短期临床预后的关系

被引：6

作者：

王双

宁梓桢

赵凯涛

吕彦

李莎莎

陈会生

机构：

[1] 沈阳军区总医院神经内科

来源：

中华老年心脑血管病杂志 | 2017年 / 19卷 / 09期

关键词：

尿素; 卒中; 组织型纤溶酶原激活物; 心房颤动; 预后;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

目的探讨入院时血尿素水平与溶栓治疗的老年急性缺血性脑卒中患者短期临床预后的关系。方法回顾性收集在我院接受重组组织型纤溶酶原激活剂静脉溶栓治疗的老年急性缺血性脑卒中患者192例。在溶栓治疗后(90±3)d应用改良的Rankin量表(mRS)评分进行神经功能预后评定,mRS评分0～2分为临床预后良好,mRS评分3～6分为临床预后不良。采用logistic回归分析计算血尿素水平与临床预后不良的关系。结果单因素logistic回归分析显示:心房颤动、血尿素、美国国立卫生研究院卒中量表(NIHSS)评分与不良临床预后相关;小动脉闭塞性脑卒中和原因不明缺血性脑卒中发生不良预后的风险相对较低。多因素logistic回归分析显示:血尿素(OR=1.309,95%CI:1.080～1.587,P=0.006)、NIHSS评分(OR=1.321,95%CI:1.205～1.447,P=0.000)、心房颤动(OR=3.782,95%CI:1.384～10.335,P=0.010)是不良临床预后的独立危险因素。结论入院时血尿素水平是溶栓治疗的老年急性缺血性脑卒中患者90d不良临床预后的独立危险因素。

引用

页码：910 / 913

页数：4

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