青年型帕金森病诊断与治疗

被引:10
作者
柏雪
胡凤云
机构
[1] 山西省人民医院神经内科
关键词
D O I
暂无
中图分类号
R742.5 [震颤麻痹综合征];
学科分类号
摘要
<正>帕金森病从传统意义上讲是一种发生在50岁以上中老年的常见的缓慢进展性运动障碍性疾病,病理学上亦被诊断为Lewy小体病,病理改变包括黑质纹状体多巴胺能神经元丢失和含a-突触核蛋白的Lewy小体形成[1]。发生帕金森病的风险是与年龄相关的,占65岁以上人群的1%2%[2]。40岁之前发病的帕金森病相对少见,约占所有住院帕金森患者的3%~
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页码:89 / 90
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共 11 条
  • [1] Deciphering the role of heterozygous mutations in genes associated with parkinsonism
    Klein, Christine
    Lohmann-Hedrich, Katja
    Rogaeva, Ekaterina
    Schlossmacher, Michael G.
    Lang, Anthony E.
    [J]. LANCET NEUROLOGY, 2007, 6 (07) : 652 - 662
  • [2] Genetics of Parkinson's disease and parkinsonism
    Hardy, John
    Cai, Huaiban
    Cookson, Mark R.
    Gwinn-Hardy, Katrina
    Singleton, Andrew
    [J]. ANNALS OF NEUROLOGY, 2006, 60 (04) : 389 - 398
  • [3] Genetics of Parkinson's disease
    Morris, HR
    [J]. ANNALS OF MEDICINE, 2005, 37 (02) : 86 - 96
  • [4] Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease
    Bozi, M
    Bhatia, KP
    [J]. MOVEMENT DISORDERS, 2003, 18 (12) : 1545 - 1547
  • [5] SIC Task Force appraisal of clinical diagnostic criteria for Parkinsonian disorders
    Litvan, I
    Bhatia, KP
    Burn, DJ
    Goetz, CG
    Lang, AE
    McKeith, I
    Quinn, N
    Sethi, KD
    Shults, C
    Wenning, GK
    [J]. MOVEMENT DISORDERS, 2003, 18 (05) : 467 - 486
  • [6] Environmental risk factors of young onset Parkinson's disease: a case-control study[J] . C.H Tsai,S.K Lo,L.C See,H.Z Chen,R.S Chen,Y.H Weng,F.C Chang,C.S Lu.Clinical Neurology and Neurosurgery . 2002 (4)
  • [7] Clinical, pathologic and genetic studies on autosomal recessive early-onset parkinsonism with diurnal fluctuation[J] . Yasuhiro Yamamura,Shigeki Kuzuhara,Kiyotarou Kondo,Tsutomu Yanagi,Masao Uchida,Hiroto Matsumine,Yoshikuni Mizuno.Parkinsonism and Related Disorders . 1998 (2)
  • [8] Mortality In Relation To Smoking: 40 Years' Observations On Male British Doctors[J] . Richard Doll,Richard Peto,Keith Wheatley,Richard Gray,Isabelle Sutherland.BMJ: British Medical Journal . 1994 (6959)
  • [9] Variable expression of Parkinson?s disease: A base-line analysis of the DAT ATOP cohort[J] . J. Jankovic,M. McDermott,J. Carter,S. Gauthier,C. Goetz,L. Golbe,S. Huber,W. Koller,C. Olanow,I. Shoulson,M. Stern,C. Tanner,W. Weiner.Neurology . 1990 (10)
  • [10] A comparison of clinical and pathological features of young- and old-onset Parkinson?s disease[J] . W. R.G. Gibb,A. J. Lees.Neurology . 1988 (9)