白细胞介素-1与缺血性脑损伤

被引:2
作者
卞杰勇
张世明
周岱
机构
[1] 苏州大学附属第一医院神经外科
关键词
白细胞介素-1; 脑缺血;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
100104 ;
摘要
白细胞介素 1(IL 1)是单个核细胞 (包括单核 -巨噬细胞和淋巴细胞 )产生的细胞因子 ,作用于淋巴细胞、巨噬细胞和其他细胞 ,通过G蛋白偶联机制发挥免疫和炎症作用。脑缺血时 ,IL 1mRNA和蛋白表达水平增高 ,炎症反应明显 ;抗IL 1能明显缩小脑梗死体积 ,减轻脑水肿 ,抑制黏附分子表达
引用
收藏
页码:300 / 302
页数:3
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