他汀类药物的临床应用进展

被引:6
作者
张兴华
林文华
机构
[1] 泰达国际心血管病医院内科
关键词
他汀类药物; 动脉粥样硬化; 冠状动脉粥样硬化性心脏病;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
1002 ; 100201 ;
摘要
他汀类药物是目前临床上应用最多的调脂药。近年来不断有证据表明,他汀类药物不仅具有调脂作用,而且可以改善内皮细胞功能,减少动脉硬化斑块中的炎性成分,具有抗炎、抗动脉粥样硬化的作用。研究证实,他汀类调脂药在冠状动脉粥样硬化性心脏病一级预防、二级预防及心脏围术期具有广泛的心血管保护作用。另外,也有研究试图探索他汀类药物对于心房颤动、心力衰竭等其他心血管疾病是否也同样具有保护作用。同时,由于其在临床的广泛的、大剂量的应用,其安全性也日益受到重视。
引用
收藏
页码:2051 / 2054
页数:4
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