Bad蛋白对细胞凋亡的调控作用

被引:21
作者
何家璇
薛荣亮
机构
[1] 西安交通大学医学院第二附属医院麻醉科
关键词
脑缺血; 凋亡; Bad蛋白; 细胞信号转导;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)]; R733.7 [白血病];
学科分类号
摘要
Bad是Bcl-2家族中与Bcl-2和Bcl-xL相关的促凋亡基因。Bcl-2家族促凋亡蛋白和抗凋亡蛋白通过竞争性相互作用来调控细胞凋亡。Bad在多种细胞中表达,近年研究表明Bad可通过细胞信号转导通路和与caspase家族成员的作用来参与细胞凋亡的全过程。其在脑缺血损伤和肿瘤方面的研究受到重视。
引用
收藏
页码:161 / 163
页数:3
相关论文
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