成人房颤急性脑梗死与非房颤急性脑梗死住院患者肾功能不全的对照分析

被引:16
作者
陈兴东
罗伟良
机构
[1] 广东医科大学附属惠州医院,广东省惠州市中心人民医院
关键词
急性脑梗死; 房颤; 肾功能不全;
D O I
暂无
中图分类号
R541.75 []; R743.33 [脑栓塞];
学科分类号
摘要
目的:比较成人心房纤颤(AF)是否比非AF急性脑梗死住院患者有较高的肾功能不全发生率,并分析可能的危险因素。方法:以本院神经内科住院的374例AF急性脑梗死患者为研究对象(AF组),随机选取同期500例非AF急性脑梗死的患者作为对照组,对比两组肾功能不全[肾小球滤过率(e GFR)<60 m L/(min·1.73 m2)]是否有差异,采用非条件Logistic回归分析AF组肾功能不全的危险因素。结果:AF组374例,肾功能不全114例(30.5%);非AF组500例,肾功能不全75例(15.0%),组间差异有统计学意义(P=0.000),比值比(OR)为2.485,AF组与非AF组的e GFR分别为(77.75±39.89)m L/(min·1.73 m2)和(96.93±39.14)m L/(min·1.73 m2)。回归分析发现AF组中导致肾功能不全的危险因素有心功能不全(OR=2.057)、高血压病(OR=1.826)、糖尿病(OR=1.897)、高尿酸血症(OR=3.161)。结论:成年AF急性脑梗死患者有肾功能不全者明显高于非AF急性脑梗死者,该组患者导致肾功能不全的危险因素有心功能不全、高血压病、糖尿病、高尿酸血症。
引用
收藏
页码:1040 / 1043
页数:4
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