脑卒中后抑郁障碍的1H-MRS研究

被引:5
作者
高勇 [1 ]
王峻 [2 ]
甄俊平 [2 ]
裴宇恒 [3 ]
牛金亮 [2 ]
机构
[1] 山西医科大学医学影像系
[2] 山西医科大学第二医院放射科
[3] 山西医科大学第二医院神经内科
关键词
抑郁症; 脑卒中; 抑郁; 磁共振波谱;
D O I
暂无
中图分类号
R749.1 [脑器质性精神障碍];
学科分类号
100205 ;
摘要
目的:探讨脑卒中后抑郁障碍(PSD)患者1H-MRS的变化特征及规律。方法:对35例脑卒中后抑郁症患者及26例健康对照组行MRI、1H-MRS扫描,兴趣区为双侧额叶背外侧白质及前部扣带回皮质。结果:①PSD组前额叶背外侧白质内Cho/Cr比值明显高于对照组(P<0.01);而NAA/Cr比值两组间差异无统计学意义(P>0.05)。②PSD组患者前额叶扣带回皮质内Cho/Cr比值明显高于对照组(P<0.01);而NAA/Cr比值两组间差异无统计学意义(P>0.05)。结论:1H-MRS能够揭示PSD时前额叶背外侧白质及扣带回皮质存在着细胞膜磷脂代谢的异常和细胞内信号转导异常。
引用
收藏
页码:7 / 9
页数:3
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