近年来,研究者发现丝裂原活化蛋白激(mitogen-activated protein kinase,MAPK)信号通路与炎症反应的关系密切,而细胞外调节蛋白激酶(extracellular-signal regulated protein kinases,ERK)是迄今为止MAPK家族中研究得较为透彻的一个成员,本文通过综述近年来关于ERK信号通路与肿瘤坏死因子α研究进展的文献,探讨ERK信号通路与炎症反应的关系。
p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials.[J].John C. Lee;Shouki Kassis;Sanjay Kumar;Alison Badger;Jerry L. Adams.Pharmacology and Therapeutics.1999, 2
p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials.[J].John C. Lee;Shouki Kassis;Sanjay Kumar;Alison Badger;Jerry L. Adams.Pharmacology and Therapeutics.1999, 2