糖化血红蛋白诊断糖尿病:知晓影响因素,合理优化使用

被引:20
作者
高冉
钟健
程歆琦
机构
[1] 中国医学科学院 北京协和医学院 北京协和医院检验科
[2] 中南大学湘雅医学院检验专业, 长沙
关键词
糖尿病; 糖化血红蛋白;
D O I
暂无
中图分类号
R587.1 [糖尿病];
学科分类号
100201 [内科学];
摘要
《中国2型糖尿病防治指南(2020年版)》中将糖化血红蛋白(HbA1c)≥6.5%纳入糖尿病的诊断标准。但一些生理和病理因素会通过改变红细胞寿命、血红蛋白糖基化速率或干扰HbA1c的检测,从而独立于血糖浓度影响HbA1c的水平。这些生理和病理因素包括贫血、慢性肾衰竭、妊娠、年龄、种族、药物等。临床医师在使用HbA1c时,需要关注这些常见的生理和病理因素,提高对HbA1c的认识。
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共 13 条
[1]
血红蛋白变异体对解读糖化血红蛋白结果的影响题录附视频 [J].
高冉 ;
程歆琦 .
中华检验医学杂志, 2019, (11)
[2]
实用内科学.[M].陈灏珠著.人民卫生出版社.2005,
[3]
Effect of ethnicity on HbA1c levels in individuals without diabetes: Systematic review and meta-analysis [J].
Cavagnolli, Gabriela ;
Pimentel, Ana Laura ;
Correa Freitas, Priscila Aparecida ;
Gross, Jorge Luiz ;
Camargo, Joiza Lins .
PLOS ONE, 2017, 12 (02)
[4]
A comparative evaluation of the analytical performances of Capillarys 2 Flex Piercing; Tosoh HLC-723 G8; Premier Hb9210; and Roche Cobas c501 Tina-quant Gen 2 analyzers for HbA determination.[J].Xiaobin Wu;Yan Chao;Zemin Wan;Yunxiu Wang;Yan Ma;Peifeng Ke;Xinzhong Wu;Jianhua Xu;Junhua Zhuang;Xianzhang Huang.Biochemia Medica.2016, 3
[5]
Glycated albumin versus glycated hemoglobin as glycemic indicator in hemodialysis patients with diabetes mellitus: Variables that influence.[J].Dawlat Sany;Yasser Elshahawy;Walid Anwar.Saudi Journal of Kidney Diseases and Transplantation.2013, 2
[6]
Racial Differences in Glycemic Markers: A Cross-sectional Analysis of Community-Based Data [J].
Selvin, Elizabeth ;
Steffes, Michael W. ;
Ballantyne, Christie M. ;
Hoogeveen, Ron C. ;
Coresh, Josef ;
Brancati, Frederick L. .
ANNALS OF INTERNAL MEDICINE, 2011, 154 (05) :303-309
[7]
Difficulties in interpreting HbA1c results [J].
Homa, Katarzyna ;
Majkowska, Liliana .
POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE, 2010, 120 (04) :148-154
[8]
Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation [J].
Khera, Paramjit K. ;
Joiner, Clinton H. ;
Carruthers, Anthony ;
Lindsell, Christopher J. ;
Smith, Eric P. ;
Franco, Robert S. ;
Holmes, Yancey R. ;
Cohen, Robert M. .
DIABETES, 2008, 57 (09) :2445-2452
[9]
Comparison of glycated albumin and hemoglobin A1c levels in diabetic subjects on hemodialysis [J].
Peacock, T. P. ;
Shihabi, Z. K. ;
Bleyer, A. J. ;
Dolbare, E. L. ;
Byers, J. R. ;
Knovich, M. A. ;
Calles-Escandon, J. ;
Russell, G. B. ;
Freedman, B. I. .
KIDNEY INTERNATIONAL, 2008, 73 (09) :1062-1068
[10]
Effect of iron deficiency anemia on the levels of hemoglobin A1c in nondiabetic patients [J].
Coban, E ;
Ozdogan, M ;
Timuragaoglu, A .
ACTA HAEMATOLOGICA, 2004, 112 (03) :126-128