Th22细胞:一种新型的辅助型T细胞

被引:5
作者
吕晶
徐军发
机构
[1] 广东医学院临床免疫学教研室
关键词
Th22细胞; IL-22;
D O I
暂无
中图分类号
R329 [人体组织学];
学科分类号
100107 [人体解剖与组织胚胎学(人体解剖学、组织与胚胎学)];
摘要
Th22细胞是最新发现的一类T辅助细胞(T-helper cell),当机体感染病毒或细菌等病原体后,T辅助细胞能够激活其他免疫细胞,并且还能帮助机体控制炎症对抗感染。研究人员发现在牛皮癣、湿疹和过敏性接触性皮炎等皮肤样品都存在有Th22细胞。Th22细胞可以产生白细胞介素22(IL-22),当发生炎症或感染时I,L-22对组织发出预警,使组织作好识别和攻击病原体的准备。Th22的发现,将为全面、深入了解辅助性T细胞的功能,寻找和开发更合理治疗慢性炎性疾病的策略提供理论依据。本文综述了Th22的发现、生物学特性以及其主要分泌因子IL-22在疾病中的作用。
引用
收藏
页码:111 / 113
页数:3
相关论文
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