力学载荷与椎间盘退变关系的研究进展

被引:12
作者
陈杰
李浩鹏
机构
[1] 西安交通大学第二附属医院骨二科
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暂无
中图分类号
R681.53 [];
学科分类号
摘要
<正>力学载荷是维持椎间盘细胞及基质的生物代谢的重要因素。椎间盘是人体内最大的无血管组织,椎间盘与周围组织的营养物质以及代谢产物的交换主要通过弥散与对流,组织间隙压力平衡的变化与渗透压的改变,为生长因子、细胞因子及酶类的运转提供泵效应[1]。椎间盘内压力变化与机体昼夜的活动有关,直立位与负重状态下对椎间盘产生较高压力载荷,而卧位时椎间盘承受的压力较小[2]。椎间盘在高压力载荷状态下产生形变,内部静水压升高,
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页码:856 / 859
页数:4
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