转录因子C/EBP β功能研究进展

被引:18
作者
蒋旭鹏 [1 ]
潘晓琳 [2 ]
潘泽民 [1 ]
机构
[1] 石河子大学医学院生物化学教研室
[2] 石河子大学新疆地方与民族高发病教育部重点实验室
关键词
转录因子; CCAAT/增强子结合蛋白β; 功能;
D O I
暂无
中图分类号
R346 [];
学科分类号
摘要
<正>CCAAT/增强子结合蛋白β(CCAAT/enhancer binding protein beta,C/EBPβ),也称作核因子白细胞介素-6(nuclear factor for IL-6,NF-IL6),是转录因子CCAAT/增强子结合蛋白(CCAAT/enhancer binding proteins,C/EBPs)家族的重要成员,其C端具有高度保守的DNA结合域和二聚化功能域,主要通过对靶细胞基因转录的调节参与细胞增殖与分化、肿瘤发生与凋亡、机体炎症反应等重要生命活动〔1〕。现就C/EBPβ的功能及对人体疾病作用机制的研究进展综述如下。
引用
收藏
页码:1628 / 1629
页数:2
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