经胸超声心动图评价左心耳封堵术对猪左心房功能及二尖瓣、肺静脉血流动力学的影响

被引:3
作者
史爱武
陆凤翔
许迪
姚静
王晓伟
盛艳辉
杨荣
李世杰
曹克将
孔祥清
机构
[1] 南京医科大学第一附属医院心血管内科
关键词
超声心动描记术; 左心房功能; 二尖瓣; 肺静脉;
D O I
暂无
中图分类号
R541.75 []; R540.45 [];
学科分类号
摘要
目的探讨左心耳封堵术对实验动物左心房功能及二尖瓣、肺静脉血流动力学的影响。方法对10只猪使用自主研制的左心耳封堵器行左心耳封堵术,分别于术前、术后1、2及4周行经胸多普勒超声心动图检查,测量左心房内径、最大及最小容积、射血分数、左心房搏出量、血流分数,二尖瓣口血流A峰峰值流速、肺静脉血流S波、D波、Ar波的峰值流速及其时间-速度积分。结果8只实验猪成功实施左心耳封堵术,手术前后超声检测左心房功能参数及二尖瓣、肺静脉血流动力学参数差异无统计学意义(P>0.05)。术前部分实验动物存在的瓣膜关闭不全现象术后无明显变化。结论左心耳封堵术后对实验动物左心房功能、二尖瓣及肺静脉血流无明显影响,长期安全性有待进一步研究。
引用
收藏
页码:67 / 69
页数:3
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