老年结肠癌患者预后影响因素分析

被引：12

作者：

李晓霞

唐元新

机构：

[1] 中国医科大学附属第四医院胃肠外科

来源：

中国普外基础与临床杂志 | 2011年 / 18卷 / 07期

关键词：

结肠肿瘤; 老年; 预后; 多因素分析;

D O I：

暂无

中图分类号：

R735.35 [];

学科分类号：

摘要：

目的探讨老年结肠癌患者临床病理特点及预后的影响因素。方法回顾性分析405例≥60岁老年结肠癌患者(老年组)的临床资料,进行预后分析并与同期收治的146例≤40岁的结肠癌患者(青年组)的临床资料进行对比。结果 2组患者在家族肿瘤史、合并疾病、术前肠梗阻及肿瘤分化程度方面的差异均有统计学(P<0.05),老年组和青年组患者术后5年生存率分别为64.9%和56.8%(P<0.05)。多因素回归分析表明,合并其他疾病、术前血清CEA值、术前肠梗阻、肿瘤大体类型、淋巴结转移、肝转移及TNM分期是影响老年结肠癌患者术后生存的独立因素。结论老年结肠癌有着独特的临床病理特点,预后较好。影响老年结肠癌患者术后生存的独立因素是合并其他疾病、术前血清CEA水平、并发肠梗阻、肿瘤大体类型、淋巴结转移、肝转移及TNM分期。

引用

页码：732 / 736

页数：5

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