基于运动想象的脑机交互康复训练新技术对脑卒中大脑可塑性影响

被引:97
作者
刘小燮 [1 ]
毕胜 [1 ]
高小榕 [2 ]
杨志 [3 ]
闫铮 [2 ]
寇程 [1 ]
马林 [4 ]
高上凯 [2 ]
机构
[1] 中国人民解放军总医院康复医学中心
[2] 清华大学医学院生物医学工程系神经工程研究所
[3] 中国科学院心理研究所行为科学重点实验室
[4] 中国人民解放军总医院放射科
关键词
脑卒中; 脑机接口; 运动想象; 功能性核磁共振; 大脑可塑性;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
目的:验证脑机接口结合功能性电刺激(BCI-FES)在中枢神经康复中的可行性及其机制。方法:对1例40岁男性脑卒中后左侧上肢重度瘫痪患者进行4周的基于运动想象的BCI-FES训练,训练前后各进行一次系统上肢功能评价及包含"运动"及"想象"组块的fMRI检测,进行功能激活图的绘制。结果:经过为期1个月的训练后左手最快抓握速度提高24.7%,左手抓握运动时功能性磁共振成像(fMRI)激活表现为出现病灶同侧主要运动区(M1)及辅助运动区(SMA)的激活,病灶对侧M1区及运动前区(PMC)激活较训练前减弱。左手运动想象任务时出现了双侧SMA及病灶同侧右后顶叶的激活。结论:脑机交互技术可促进脑卒中患者的中枢神经重塑。BCI-FES应用于存在脑损伤的脑卒中患者的康复训练是可行的。
引用
收藏
页码:97 / 102
页数:6
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