富血小板血浆的制备与临床应用研究进展

被引:18
作者
谢雪涛
施忠民
张长青
机构
[1] 上海交通大学附属第六人民医院骨科
关键词
D O I
暂无
中图分类号
R457 [血液疗法];
学科分类号
100231 [临床病理学];
摘要
<正>富血小板血浆(platelet-rich plasma,PRP)是通过离心法从周围全血中分离出的血小板浓缩物,根据制作方法的不同,可能同时含有高浓度的白细胞和纤维蛋白原等。血小板在激活后会释放多种生长因子,如转化生长因子-β、胰岛素样生长因子、血小板源性生长因子、表皮生长因子、血管内皮生长因子和碱性成纤维细胞生长因子(basic fibroblast growth factor,b-FGF)等,这些生长因子可刺激细胞的增殖、合成与代
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