间充质干细胞衰老的研究进展

被引:2
作者
张琳琳 [1 ]
毕春升 [1 ]
陈发明 [1 ]
金岩 [2 ]
机构
[1] 第四军医大学口腔医院军事口腔医学国家重点实验室牙周病科
[2] 第四军医大学口腔医院军事口腔医学国家重点实验室组织工程研发中心
关键词
间充质干细胞; 衰老; 端粒酶;
D O I
10.15956/j.cnki.chin.j.conserv.dent.2014.12.013
中图分类号
R329 [人体组织学];
学科分类号
100107 [人体解剖与组织胚胎学(人体解剖学、组织与胚胎学)];
摘要
衰老是指机体各器官在功能上普遍而逐渐降低的过程,主要表现为自身抵抗能力的降低以及对外界环境刺激的反应能力降低,从而诱发疾病的易感性最终引起死亡。在机体衰老的过程中,由于受到病理、环境等因素的刺激,间充质干细胞的自我调节机制发生异常改变,从而使得其某些生物学性状不再稳定。本文就间充质干细胞在衰老过程中的变化及诱发这种变化的原因等方面的研究进展作一综述。
引用
收藏
页码:734 / 737
页数:4
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