神经细胞内钙超载与阿尔茨海默病关系的研究进展

被引:3
作者
周晓辉
徐明明
机构
[1] 新疆医科大学第一附属医院干部心血管一科
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中图分类号
R686 [筋腱、韧带、滑囊疾病及损伤];
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摘要
<正>阿尔茨海默病(AD)亦名老年性痴呆(senile dementia),是以进行性痴呆为特征的大脑退行性变性疾病。AD发病率从以往每年低于3%增至目前的4%以上,85岁以上的老年人发病率达40%。AD的特征性病理改变是神经元细胞外有大量神经炎性空斑(extra cellular neurotic plaque)即老年斑(senileplaques,SPs)及神经元细胞内有神经纤维缠结(neuro fibrillary tangles,NFTs)的释放。
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