共 19 条
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Troglitazone quinone formation catalyzed by human and rat CYP3A:an typical CYP oxidation reaction. He K,Woolf TF,Kindt EK,et al. Biochemical Pharmacology . 2001
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Expression of CYP3A,CYP2B6,and CYP2C9is regulated by the Vitamin D receptor pathway in primary human hepatocyte. Lionel D,Ourlin JC,Pascussi JM,et al. Journal of Biological Chemistry . 2002
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The orphan nuclear receptor HNF4αdetermines PXR-and CAR-mediated xenobiotic induction of CYP3A4. Rommel G,Lee W,Brenda F,et al. Nature Medicine . 2003
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Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression. Phillips A,Hood SR,Gibson GG,et al. Drug Metabolism and Disposition . 2005
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Indinavir concentrations and St John’s wort. Piscitelli SC,Burstein AH,Chaitt D,et al. The Lancet . 2000
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Two CCAAT/enhancer binding protein sites in the cytochrome P4503A1locus. Rodrigues E,Vilarem MJ,Ribeiro V,et al. European Journal of Biochemistry . 2003
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The pregnane X receptor binds to response elements in a genomic context-dependent manner and PXR activators rifampicin selectively alters the binding among target genes. Song X,Xie M,Zhang H,et al. Drug Metabolism and Disposition . 2004
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Role of Sp1,C/EBPα,HNF3and PXR in the basal-and xenobiotic-mediated regulation of the CYP3A4gene. Vicent B,Kevin T,Gordon G,et al. Drug Metabolism and Disposition . 2004
[9]
The human pregnane X receptor:genomic structure and identification and functional characterization of natural allelic variants. Zhang J,Kuehl P,Green ED,et al. Pharmacogenetics . 2001
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The environmental pollutant1,1-dichoro-2,2-bis ethylene induces rat hepatic cytochrome P4502B and3A expression through the constituteive androstane receptorand pregnane X receptor. Michale EW,Erika B,Akiko U,et al. Molecular Pharmacology . 2003