埃索美拉唑的临床应用与安全性

被引:10
作者
祝锡聪
机构
[1] 山西博爱医院
关键词
埃索美拉唑; 抑酸; 安全用药;
D O I
暂无
中图分类号
R96 [药理学];
学科分类号
100602 ; 100706 ;
摘要
<正>埃索美拉唑(商品名耐信)为质子泵抑制药。质子泵抑制药(PPI)在临床上用于治疗各种酸相关性疾病,如消化性溃疡(包括应激性溃疡)、胃食管反流病(包括反流性食管炎)、胃泌素瘤、部分功能性消化不良等疾病。由于作用部位是胃黏膜壁细胞分泌胃酸的最后步骤质子泵,即壁细胞内的H+- K+-ATP酶,从而抑制基础胃酸及各种刺激所致的
引用
收藏
页码:215 / 217
页数:3
相关论文
共 8 条
[1]   埃索美拉唑致面部浮肿1例 [J].
李贤福 .
中国新药杂志, 2005, (03) :368-368
[2]   酸相关疾病治疗的抑酸水平及药物选择 [J].
李瑜元 .
中华消化杂志, 2001, (11) :1-2
[3]   北京上海胃食管反流症状的流行病学调查 [J].
潘国宗 ;
许国铭 ;
郭慧平 ;
柯美云 ;
韩少梅 ;
李兆申 ;
方秀才 ;
邹多武 ;
鲁素彩 ;
刘婧 .
中华消化杂志, 1999, (04) :8-11
[4]  
Esomeprazole 40?mg i.v. provides faster and more effective intragastric acid control than pantoprazole 40?mg i.v.: results of a randomized study[J] . Alimentary Pharmacology & Therapeutics . 2004 (10)
[5]   Effect of splitting the dose of esomeprazole on gastric acidity and nocturnal acid breakthrough [J].
Hammer, J ;
Schmidt, B .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2004, 19 (10) :1105-1110
[6]  
Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study[J] . Philip Miner,Philip O Katz,Yusong Chen,Mark Sostek.The American Journal of Gastroenterology . 2003 (12)
[7]  
Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial[J] . Joel E. Richter,Peter J. Kahrilas,John Johanson,Paul Maton,Jeffrey R. Breiter,Clara Hwang,Victoria Marino,Bernard Hamelin,Jeffrey G. Levine.The American Journal of Gastroenterology . 2001 (3)
[8]  
Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety[J] . David A Johnson,Stanley B Benjamin,Nimish B Vakil,Jay L Goldstein,Mark Lamet,James Whipple,Donald D’Amico,Bernard Hamelin.The American Journal of Gastroenterology . 2001 (1)