小鼠肝炎病毒的研究近况

被引:13
作者
付红焱
徐波
宫泽辉
机构
[1] 军事医学科学院毒物药物研究所
关键词
MHVA59病毒; 免疫调节; 结构与机制;
D O I
暂无
中图分类号
R373.2 [肠道病毒与肝炎病毒];
学科分类号
摘要
小鼠肝炎病毒 (micehepatitisvirus ,MHV)是一种日冕冠状病毒 ,具有嗜神经性 ,可引起啮齿动物急慢性神经性疾病。可通过血液、脑脊液和消化液等渠道传播 ,引起肠炎、肝炎、胸腺退化、多发性硬化症、脱髓鞘性脑脊髓炎等疾病 ,同时它也能刺激B淋巴细胞分泌抗体。目前国内对其研究的还很少 ,国外报道的也不多。本综述的意图是通过对MHV冠状病毒感染机制的探讨 ,以有助于指导抗病毒的有效药物的筛选
引用
收藏
页码:367 / 370
页数:4
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