茯苓素对小鼠白血病L1210细胞的抑制作用

被引:25
作者
许津
吕丁
钟启平
机构
[1] 中国医学科学院医药生物技术研究所,中国医学科学院医药生物技术研究所,中国医学科学院医药生物技术研究所北京,北京,北京
关键词
茯苓素; 白血病L1210细胞; 核苷转运;
D O I
暂无
中图分类号
学科分类号
摘要
本文报道中药茯苓提取物——茯苓素体外对小鼠白血病L1210细胞的抑制作用,对L1210细胞DNA合成的补偿途径各个环节的作用。实验表明,茯苓素可明显抑制细胞膜对核苷的转运,对胸苷激酶的抑制作用较弱,但对DNA聚合酶则无影响。提示茯苓素对核苷转运的作用可能是抑制DNA合成的一个重要环节。
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页码:45 / 49
页数:5
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