女性抑郁状态患者海马形态体积的变化

被引:13
作者
李月峰 [1 ]
罗香 [2 ]
王冬青 [1 ]
李国海 [2 ]
姜平 [3 ]
尉传社 [1 ]
彭卫斌 [1 ]
李阳 [3 ]
殷瑞根 [1 ]
赵亮 [1 ]
机构
[1] 江苏大学基础医学与医学技术学院附属医院影像科
[2] 江苏大学基础医学与医学技术学院附属四院精神科
[3] 江苏大学基础医学与医学技术学院脑功能与影像研究室
关键词
抑郁; 海马; 磁共振成像;
D O I
暂无
中图分类号
R749.4 [情感性精神病];
学科分类号
100204 [神经病学];
摘要
目的探讨女性抑郁患者的双侧海马及其各部形态体积变化的特点。方法采用3.0 T磁共振,分别测量女性抑郁患者(30例,抑郁组)及对照组(30名)的海马及其各部体积和层数。结果 (1)抑郁组左侧海马头平均层面积(121±33)mm2,小于对照组的(148±32)mm2;层数(14.9±3.2)层,多于对照组的(12.3±3.1)层;P均<0.01;抑郁组左右侧尾部层数[(5.9±2.6)层,(6.4±1.8)层]少于对照组[(7.7±2.5)层,(7.8±2.3)层],P<0.05。(2)抑郁组左右侧海马体积[(3164±218)mm3,(3202±202)mm3]小于对照组[(3324±334)mm3,(3338±301)mm3],P<0.05,海马左右侧尾体积[(384±120)mm3,(414±101)mm3]亦小于对照组[(498±134)mm3,(501±121)mm3],P<0.01。结论左侧海马头部形态改变和两侧海马尾体积缩小及其形态改变可能是女性抑郁患者的特征之一。
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